Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro

From OmniJournal
Revision as of 17:09, 22 July 2020 by Jtodaro2 (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
  • Jia Liu
  • Ruiyuan Cao
  • Mingyue Xu
  • ...
  • Manli Wang
Journal Cell Discovery
Date March 18, 2020

In vitro study demonstrating that hydroxychloroquine is effective in inhibiting SARS-CoV-2 infection by blocking the transport of SARS-CoV-2 from EEs to Els, which is a requirement to release the viral genome. Authors conclude that hydroxychloroquine’s in vitro effect of inhibiting viral replication in combination with its anti-inflammatory function makes the drug a good candidate for treatment of COVID-19.

Major Issues

No major issues identified at this time.

Minor Issues

No minor issues identified at this time.


This study demonstrated in vitro efficacy of hydroxychloroquine in blocking a necessary step in viral replication of SARS-CoV-2.

Article Revisions

None at this time.