Talk:Gilead: Twenty-one billion reasons to discredit hydroxychloroquine (ORIGINAL ARTICLE)

From OmniJournal
Jump to navigation Jump to search

Excellent article, well written. In the intitial phase of the COVID-19 pandemic repurposing of drugs was essential. Both hydroxychloroquine as well as azithromycin had known effects on viral replication in vitro and their use was therefore an obvious choice. It is also obvious that controlled trials are not possible in this situation and for a newly emerged pathogen historical controls don't work either. Both drugs have an excellent safety record, HCQ having been used on millions of persons for malaria prophylaxis. It is unclear why this potentially lifesaving treatment has been discredited. The article above gives a disquieting but plausible explanation. I would encourage to read the plea for use of HCQ (combined with azithromycin or tetracycline) in outpatients: https://doi.org/10.1093/aje/kwaa093